Colistimethate sodium for injection and inhalation (Colistin Leaflet) Each Injection contains: Composition: Colistin Colistimethate sodium injection Colistin 1 MIU Each vial contains: 1 Million International Units (1 MIU) Colistimethate Sodium DOSAGE : Powder for solution for injection, infusion and inhalation Mode of Action : Colistimethate sodium is a cyclic polypeptide antibiotic derived from Bacillus polymyxa var. colistinus and belongs to the polymyxin group. The polymyxin antibiotics are cationic surface-active agents that work by damaging the cell membrane. The resulting physiological effects are lethal to the bacterium. Polymyxins are